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Fig. 4 | Retrovirology

Fig. 4

From: The envelope proteins from SARS-CoV-2 and SARS-CoV potently reduce the infectivity of human immunodeficiency virus type 1 (HIV-1)

Fig. 4

Restriction of infectious HIV-1 production by the SARS-CoV, MERS-CoV, and HCoV-OC43 E proteins. A The level of infectious HIV-1 released into the culture medium from cells co-transfected with pcDNA3.1( +) alone, or vectors expressing SARS-CoV-2 E-HA, SARS-CoV E-HA, MERS-CoV E-HA, HCoV-OC43 E-HA, HSV-1 gD, or gD[ΔTMCT] and pNL4-3. B Immunoprecipitation of gD and gD[ΔTMCT] from the cell lysates of the restriction assay in Panel A using an anti-gD antibody. C Immunoprecipitation of the various E proteins from the cell lysates from the restriction assay in Panel A using an anti-HA antibody

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