Fig. 9
From: Rotten to the core: antivirals targeting the HIV-1 capsid core
HIV-1 CA central pore binding site. A CA hexamer (PDB ID: 4XFX) is shown with CANTDs in light gray and light cyan, CACTDs in dark gray and dark cyan, and R18 side chains at the sixfold symmetry axis in alternating blue and light blue colors. B IP6 (brown sticks) is shown bound to CA hexamer (PDB ID: 6BHT). Right, IP6 above and below R18 ring. C Hexacarboxybenzene (HCB; magenta sticks) bound to CA hexamer (PDB ID: 5HGP). Right, HCB interacting with R18