Fig. 1
From: Rotten to the core: antivirals targeting the HIV-1 capsid core
(Part C of this figure is based on Fig. 1 from Gres et al. [105]. Reprinted with permission from AAAS)
Structure of mature HIV-1 CA. A The HIV-1 CA monomer comprises CANTD (light gray) and CACTD (dark gray) domains (PDB ID: 4XFX). The view is rotated by 180°. B The same domains are shown in the context of the HIV-1 CA hexamer. Colors are as described in A, with neighboring CANTDʹ and CACTDʹ domains shown as light and dark cyan, respectively. The views are rotated by 90°. C Schematic outlining the sequence and secondary structural elements of HIV-1 CA (based on PDB ID: 4XFX)