Fig. 6
From: NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase
![Fig. 6](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12977-019-0492-z/MediaObjects/12977_2019_492_Fig6_HTML.png)
Effect of DNA-PKcs inhibitor Nu7441 on luciferase expression in primary human PBMCs. Cells were isolated from whole blood, activated and transductions were performed 48 h later with 0.1 MOI of either HIV_wt or HIV_mut in the presence of 7 µg/mL polybrene. Luciferase expression was assayed 48 h after transduction. Left plot: data is normalized to the luciferase expression level in DMSO-treated cells transduced by HIV_wt; right plot: luciferase expression level in Nu7441 treated cells is normalized to the luciferase level in DMSO-treated cells for each pseudovirus separately. Means and SDs of (n = 5) are presented. Significance was determined by two-tailed Student’s t-test, * = p < 0.05