Figure 4
From: BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid
BI-2 blocks HIV-1 and SIV mac infection. Cf2Th cells were challenged with increasing amount of the indicated retrovirus in the presence of BI-2. Infection was determined by measuring the percentage of GFP-positive cells by flow cytometry 48Â hours post infection. As control, we performed similar experiments in the presence of the small-molecule PF74. Similar results were obtained in three independent experiments and a representative experiment is shown.