Figure 1

Sequence alignment of HIV-2rod and SIVmne Vpx. The amino acid sequence of HIV-2 strain ROD10/ES Vpx is provided with differences present in SIVmne indicated, and dashes representing residues identical in both Vpx products. Tyrosine residues subjected to mutation in SIV-X(y-a) are underlined, and their codon numbers are indicated above each residue. Pro residues 103-104 are underlined since they were substituted with termination codons in SIV-X(102), with the C-terminal Gly residue in the predicted truncated protein indicated by the number above the residue.