Figure 2
From: Disease-associated XMRV sequences are consistent with laboratory contamination
Phylogeny of 22Rv1 and patient derived XMRV sequences and other murine leukaemia viruses. Bayesian maximum clade credibility phylogeny of 22Rv1 cell line derived XMRV clones, patient derived XMRV sequences and other murine leukaemia viruses (A). The monophyletic cluster formed by 22Rv1 cell line derived XMRV clones and patient derived XMRVs is magnified in ( B ). Xenotropic MLV (MLV-X), polytropic MLV (PMLV), and modified polytropic MLV (MPMLV) were added as controls. Sequences derived from prostate cancer patients (VP and WO) and chronic fatigue syndrome patients (WPI) are indicated by red and yellow circles respectively. Gene sequences derived from 22Rv1 clones are indicated by blue squares. When full-length genomes were not available, the loci of the sequence used in the phylogenetic reconstruction are shown in brackets. APOBEC-3G/F hypermutated clones are labelled with a closed circle. The tree is rooted against AKV and Moloney MLVs. Bayesian posterior probabilities of 1.00 are indicated on the corresponding branches by a star. The scale bar represents the number of nucleotide substitutions per site.