Figure 1From: Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infectionClinical data and experimental protocol for patient CH078. CH078 was HIV-1 viral RNA positive, antibody negative (Fiebig I/II) at screening. The plasma VL (red points and black line) and CD4+ T cell counts (blue points and line) are shown. pVL declined rapidly by ~2 log within the first 28 days from screening. Next pVL stabilized from days 28-77, followed by another period of slower pVL decline of ~1 log over several months to establish a setpoint of 3,520 copies/ml around 6 months post-screening. Samples were used for SGA sequencing (orange arrows), T cell ELISpot (purple arrows), and flow cytometry (green arrows) at the timepoints indicated.Back to article page